The nature and nurture of cell heterogeneity: accounting for macrophage gene-environment interactions with single-cell RNA-Seq

BACKGROUND: Single-cell RNA-Seq can be a valuable and unbiased tool to dissect cellular heterogeneity, despite the transcriptome’s limitations in describing higher functional phenotypes and protein events. Perhaps the most important shortfall with transcriptomic ‘snapshots’ of cell populations is th...

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Publicat a:BMC Genomics
Autors principals: Wills, Quin F., Mellado-Gomez, Esther, Nolan, Rory, Warner, Damien, Sharma, Eshita, Broxholme, John, Wright, Benjamin, Lockstone, Helen, James, William, Lynch, Mark, Gonzales, Michael, West, Jay, Leyrat, Anne, Padilla-Parra, Sergi, Filippi, Sarah, Holmes, Chris, Moore, Michael D., Bowden, Rory
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Methodology Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5219790/
https://ncbi.nlm.nih.gov/pubmed/28061811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3445-0
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