A poxvirus protein forms a complex with left-handed Z-DNA: Crystal structure of a Yatapoxvirus Zα bound to DNA

A conserved feature of poxviruses is a protein, well characterized as E3L in vaccinia virus, that confers IFN resistance on the virus. This protein comprises two domains, an N-terminal Z-DNA-binding protein domain (Zα) and a C-terminal double-stranded RNA-binding domain. Both are required for pathog...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Ha, Sung Chul, Lokanath, Neratur K., Van Quyen, Dong, Wu, Chun Ai, Lowenhaupt, Ky, Rich, Alexander, Kim, Yang-Gyun, Kim, Kyeong Kyu
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC521960/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15448208/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0405586101
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