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A peptide with alternating lysines can act as a highly specific Z-DNA binding domain
Many nucleic acid binding proteins use short peptide sequences to provide specificity in recognizing their targets, which may be either a specific sequence or a conformation. Peptides containing alternating lysine have been shown to bind to poly(dG–d5meC) in the Z conformation, and stabilize the hig...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1635270/ https://ncbi.nlm.nih.gov/pubmed/16982643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl607 |
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