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Restoration of an absent G(1) arrest and protection from apoptosis in embryonic stem cells after ionizing radiation

Response to DNA damage and cell-cycle regulation differ markedly between embryonic stem (ES) cells and somatic cells. ES cells require exquisitely sensitive mechanisms to maintain genomic integrity and do so, in part, by suppressing spontaneous mutation. Spontaneous mutation frequency in somatic cel...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Hong, Yiling, Stambrook, Peter J.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2004
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC521944/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15452351/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0401346101
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