Efficacy of PLD-118, a Novel Inhibitor of Candida Isoleucyl-tRNA Synthetase, against Experimental Oropharyngeal and Esophageal Candidiasis Caused by Fluconazole-Resistant C. albicans

PLD-118, formerly BAY 10-8888, is a synthetic antifungal derivative of the naturally occurring β-amino acid cispentacin. We studied the activity of PLD-118 in escalating dosages against experimental oropharyngeal and esophageal candidiasis (OPEC) caused by fluconazole (FLC)-resistant Candida albican...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Petraitis, Vidmantas, Petraitiene, Ruta, Kelaher, Amy M., Sarafandi, Alia A., Sein, Tin, Mickiene, Diana, Bacher, John, Groll, Andreas H., Walsh, Thomas J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2004
Pynciau:
Experimental Therapeutics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC521932/
https://ncbi.nlm.nih.gov/pubmed/15388459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.3959-3967.2004
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg