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Dual-Action Mechanism of Viramidine Functioning as a Prodrug and as a Catabolic Inhibitor for Ribavirin

An investigational nucleoside analogue drug, viramidine, has recently emerged as a potentially safer alternative to ribavirin for the treatment of hepatitis C viral infection. We have reported that viramidine mainly functions as a prodrug of ribavirin that is enriched in the liver. This in vitro stu...

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Bibliografiske detaljer
Main Authors: Wu, Jim Zhen, Larson, Gary, Hong, Zhi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC521899/
https://ncbi.nlm.nih.gov/pubmed/15388466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.4006-4008.2004
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