Genomic Approach to Identification of Mutations Affecting Caspofungin Susceptibility in Saccharomyces cerevisiae

The antifungal agent caspofungin (CAS) specifically interferes with glucan synthesis and cell wall formation. To further study the cellular processes affected by CAS, we analyzed a Saccharomyces cerevisiae mutant collection (4,787 individual knockout mutations) to identify new genes affecting suscep...

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Bibliographic Details
Main Authors: Markovich, Sarit, Yekutiel, Aya, Shalit, Itamar, Shadkchan, Yona, Osherov, Nir
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC521896/
https://ncbi.nlm.nih.gov/pubmed/15388447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.3871-3876.2004
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