Genomic Approach to Identification of Mutations Affecting Caspofungin Susceptibility in Saccharomyces cerevisiae

The antifungal agent caspofungin (CAS) specifically interferes with glucan synthesis and cell wall formation. To further study the cellular processes affected by CAS, we analyzed a Saccharomyces cerevisiae mutant collection (4,787 individual knockout mutations) to identify new genes affecting suscep...

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Hauptverfasser: Markovich, Sarit, Yekutiel, Aya, Shalit, Itamar, Shadkchan, Yona, Osherov, Nir
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Mechanisms of Action: Physiological Effects
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC521896/
https://ncbi.nlm.nih.gov/pubmed/15388447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.3871-3876.2004
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