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Antibodies Targeting Closely Adjacent or Minimally Overlapping Epitopes Can Displace One Another
Here we describe how real-time label-free biosensors can be used to identify antibodies that compete for closely adjacent or minimally overlapping epitopes on their specific antigen via a mechanism of antibody displacement. By kinetically perturbing one another’s binding towards their antigen via th...
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| Publicado en: | PLoS One |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5218414/ https://ncbi.nlm.nih.gov/pubmed/28060885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169535 |
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