Assessing kinetic and epitopic diversity across orthogonal monoclonal antibody generation platforms

The ability of monoclonal antibodies (mAbs) to target specific antigens with high precision has led to an increasing demand to generate them for therapeutic use in many disease areas. Historically, the discovery of therapeutic mAbs has relied upon the immunization of mammals and various in vitro dis...

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Hlavní autoři: Abdiche, Yasmina Noubia, Harriman, Rian, Deng, Xiaodi, Yeung, Yik Andy, Miles, Adam, Morishige, Winse, Boustany, Leila, Zhu, Lei, Izquierdo, Shelley Mettler, Harriman, William
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966639/
https://ncbi.nlm.nih.gov/pubmed/26652308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1118596
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