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Molecular Mechanisms of Attenuation of the Sabin Strain of Poliovirus Type 3

Mutations critical for the central nervous system (CNS) attenuation of the Sabin vaccine strains of poliovirus (PV) are located within the viral internal ribosome entry site (IRES). We examined the interaction of the IRESs of PV type 3 (PV3) and Sabin type 3 (Sabin3) with polypyrimidine tract-bindin...

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書誌詳細
出版年:J Virol
主要な著者: Guest, Stephen, Pilipenko, Evgeny, Sharma, Kamal, Chumakov, Konstantin, Roos, Raymond P.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC521805/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15452230/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.20.11097-11107.2004
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