Molecular Mechanisms of Attenuation of the Sabin Strain of Poliovirus Type 3

Mutations critical for the central nervous system (CNS) attenuation of the Sabin vaccine strains of poliovirus (PV) are located within the viral internal ribosome entry site (IRES). We examined the interaction of the IRESs of PV type 3 (PV3) and Sabin type 3 (Sabin3) with polypyrimidine tract-bindin...

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Bibliographische Detailangaben
Hauptverfasser: Guest, Stephen, Pilipenko, Evgeny, Sharma, Kamal, Chumakov, Konstantin, Roos, Raymond P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC521805/
https://ncbi.nlm.nih.gov/pubmed/15452230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.20.11097-11107.2004
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