Molecular Mechanisms of Attenuation of the Sabin Strain of Poliovirus Type 3

Mutations critical for the central nervous system (CNS) attenuation of the Sabin vaccine strains of poliovirus (PV) are located within the viral internal ribosome entry site (IRES). We examined the interaction of the IRESs of PV type 3 (PV3) and Sabin type 3 (Sabin3) with polypyrimidine tract-bindin...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Guest, Stephen, Pilipenko, Evgeny, Sharma, Kamal, Chumakov, Konstantin, Roos, Raymond P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2004
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC521805/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15452230/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.20.11097-11107.2004
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