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Molecular Mechanisms of Attenuation of the Sabin Strain of Poliovirus Type 3
Mutations critical for the central nervous system (CNS) attenuation of the Sabin vaccine strains of poliovirus (PV) are located within the viral internal ribosome entry site (IRES). We examined the interaction of the IRESs of PV type 3 (PV3) and Sabin type 3 (Sabin3) with polypyrimidine tract-bindin...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC521805/ https://ncbi.nlm.nih.gov/pubmed/15452230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.20.11097-11107.2004 |
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