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AMP-activated Kinase (AMPK) Promotes Innate Immunity and Antiviral Defense through Modulation of Stimulator of Interferon Genes (STING) Signaling

The host protein Stimulator of Interferon Genes (STING) has been shown to be essential for recognition of both viral and intracellular bacterial pathogens, but its regulation remains unclear. Previously, we reported that mitochondrial membrane potential regulates STING-dependent IFN-β induction inde...

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Pubblicato in:J Biol Chem
Autori principali: Prantner, Daniel, Perkins, Darren J., Vogel, Stefanie N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217687/
https://ncbi.nlm.nih.gov/pubmed/27879319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.763268
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