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Type I interferon Licenses Enhanced Innate Recognition and Transcriptional Responses to Franciscella tularensis LVS

The innate inflammatory response to Francisella tularensis (Ft) in macrophages is significantly governed by the expression of type I interferons (IFN). Previously, the proteolytic processing and maturation of pro-IL-1β protein was shown to depend upon type I IFN expression. We show in this report th...

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Detalhes bibliográficos
Publicado no:Innate Immun
Main Authors: Richard, Katharina, Vogel, Stefanie N., Perkins, Darren J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955828/
https://ncbi.nlm.nih.gov/pubmed/27231145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425916650027
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