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AMP-activated Kinase (AMPK) Promotes Innate Immunity and Antiviral Defense through Modulation of Stimulator of Interferon Genes (STING) Signaling

The host protein Stimulator of Interferon Genes (STING) has been shown to be essential for recognition of both viral and intracellular bacterial pathogens, but its regulation remains unclear. Previously, we reported that mitochondrial membrane potential regulates STING-dependent IFN-β induction inde...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Prantner, Daniel, Perkins, Darren J., Vogel, Stefanie N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217687/
https://ncbi.nlm.nih.gov/pubmed/27879319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.763268
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