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Targeted inhibition in tumors with ALK dependency

The oncogenic function of gene translocations involving the anaplastic lymphoma kinase (ALK) was first reported in rare subtypes of non-Hodgkin’s lymphoma almost two decades ago. More recently, aberrant ALK signaling was found to be an oncogenic driver in subsets of non-small cell lung cancer (NSCLC...

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Foilsithe in:Lung Cancer (Auckl)
Main Authors: Kwak, Eunice L, Clark, Jeffrey W, Shaw, Alice T
Formáid: Artigo
Teanga:Inglês
Foilsithe: Dove Medical Press 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217435/
https://ncbi.nlm.nih.gov/pubmed/28210129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/LCTT.S16313
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