Peptides derived from the dependence receptor ALK are proapoptotic for ALK-positive tumors

ALK is a receptor tyrosine kinase with an oncogenic role in various types of human malignancies. Despite constitutive activation of the kinase through gene alterations, such as chromosomal translocation, gene amplification or mutation, treatments with kinase inhibitors invariably lead to the develop...

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Vydáno v:Cell Death Dis
Hlavní autoři: Aubry, A, Galiacy, S, Ceccato, L, Marchand, C, Tricoire, C, Lopez, F, Bremner, R, Racaud-Sultan, C, Monsarrat, B, Malecaze, F, Allouche, M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669685/
https://ncbi.nlm.nih.gov/pubmed/25950466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.102
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