Peptides derived from the dependence receptor ALK are proapoptotic for ALK-positive tumors

ALK is a receptor tyrosine kinase with an oncogenic role in various types of human malignancies. Despite constitutive activation of the kinase through gene alterations, such as chromosomal translocation, gene amplification or mutation, treatments with kinase inhibitors invariably lead to the develop...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Dis
Egile Nagusiak: Aubry, A, Galiacy, S, Ceccato, L, Marchand, C, Tricoire, C, Lopez, F, Bremner, R, Racaud-Sultan, C, Monsarrat, B, Malecaze, F, Allouche, M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2015
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669685/
https://ncbi.nlm.nih.gov/pubmed/25950466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.102
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