Peptides derived from the dependence receptor ALK are proapoptotic for ALK-positive tumors

ALK is a receptor tyrosine kinase with an oncogenic role in various types of human malignancies. Despite constitutive activation of the kinase through gene alterations, such as chromosomal translocation, gene amplification or mutation, treatments with kinase inhibitors invariably lead to the develop...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Aubry, A, Galiacy, S, Ceccato, L, Marchand, C, Tricoire, C, Lopez, F, Bremner, R, Racaud-Sultan, C, Monsarrat, B, Malecaze, F, Allouche, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669685/
https://ncbi.nlm.nih.gov/pubmed/25950466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.102
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