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Diagnosis and Treatment of ALK Positive NSCLC

Anaplastic lymphoma kinase (ALK) gene rearrangements occur in a small portion of patients with non-small cell lung cancer (NSCLC). These gene rearrangements lead to constitutive activation of the ALK kinase and subsequent ALK driven tumor formation. Patients with tumors harboring such rearrangements...

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Bibliographic Details
Published in:Hematol Oncol Clin North Am
Main Authors: Arbour, Kathryn C., Riely, Gregory J.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154547/
https://ncbi.nlm.nih.gov/pubmed/27912826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hoc.2016.08.012
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