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ALK in Lung Cancer: Past, Present, and Future
In 2007, scientists discovered that anaplastic lymphoma kinase (ALK) gene rearrangements are present in a small subset of non–small-cell lung cancers. ALK-positive cancers are highly sensitive to small-molecule ALK kinase inhibitors, such as crizotinib. Phase I and II studies of crizotinib in ALK-po...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Clinical Oncology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4209068/ https://ncbi.nlm.nih.gov/pubmed/23401436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2012.44.5353 |
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