Concurrent Label-Free Mass Spectrometric Analysis of Dystrophin Isoform Dp427 and the Myofibrosis Marker Collagen in Crude Extracts from mdx-4cv Skeletal Muscles

The full-length dystrophin protein isoform of 427 kDa (Dp427), the absence of which represents the principal abnormality in X-linked muscular dystrophy, is difficult to identify and characterize by routine proteomic screening approaches of crude tissue extracts. This is probably related to its large...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proteomes
Prif Awduron: Murphy, Sandra, Zweyer, Margit, Mundegar, Rustam R., Henry, Michael, Meleady, Paula, Swandulla, Dieter, Ohlendieck, Kay
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217383/
https://ncbi.nlm.nih.gov/pubmed/28248273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/proteomes3030298
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