Label-free mass spectrometric analysis reveals complex changes in the brain proteome from the mdx-4cv mouse model of Duchenne muscular dystrophy

BACKGROUND: X-linked muscular dystrophy is a primary disease of the neuromuscular system. Primary abnormalities in the Dmd gene result in the absence of the full-length isoform of the membrane cytoskeletal protein dystrophin. Besides progressive skeletal muscle wasting and cardio-respiratory complic...

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Détails bibliographiques
Publié dans:Clin Proteomics
Auteurs principaux: Murphy, Sandra, Zweyer, Margit, Henry, Michael, Meleady, Paula, Mundegar, Rustam R., Swandulla, Dieter, Ohlendieck, Kay
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657206/
https://ncbi.nlm.nih.gov/pubmed/26604869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12014-015-9099-0
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