Proteomic profiling of mdx-4cv serum reveals highly elevated levels of the inflammation-induced plasma marker haptoglobin in muscular dystrophy

X-linked muscular dystrophy is caused by primary abnormalities in the Dmd gene and is characterized by the almost complete loss of the membrane cytoskeletal protein dystrophin, which triggers sarcolemmal instability, abnormal calcium homeostasis, increased proteolysis and impaired excitation-contrac...

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Publicat a:Int J Mol Med
Autors principals: Murphy, Sandra, Dowling, Paul, Zweyer, Margit, Henry, Michael, Meleady, Paula, Mundegar, Rustam R., Swandulla, Dieter, Ohlendieck, Kay
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2017
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428965/
https://ncbi.nlm.nih.gov/pubmed/28440464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2017.2952
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