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Simultaneous Pathoproteomic Evaluation of the Dystrophin-Glycoprotein Complex and Secondary Changes in the mdx-4cv Mouse Model of Duchenne Muscular Dystrophy

In skeletal muscle, the dystrophin-glycoprotein complex forms a membrane-associated assembly of relatively low abundance, making its detailed proteomic characterization in normal versus dystrophic tissues technically challenging. To overcome this analytical problem, we have enriched the muscle membr...

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Detalhes bibliográficos
Publicado no:Biology (Basel)
Main Authors: Murphy, Sandra, Henry, Michael, Meleady, Paula, Zweyer, Margit, Mundegar, Rustam R., Swandulla, Dieter, Ohlendieck, Kay
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498307/
https://ncbi.nlm.nih.gov/pubmed/26067837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology4020397
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