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Targeted inhibition of STATs and IRFs as a potential treatment strategy in cardiovascular disease

Key factors contributing to early stages of atherosclerosis and plaque development include the pro-inflammatory cytokines Interferon (IFN)α, IFNγ and Interleukin (IL)-6 and Toll-like receptor 4 (TLR4) stimuli. Together, they trigger activation of Signal Transducer and Activator of Transcription (STA...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Szelag, Malgorzata, Piaszyk-Borychowska, Anna, Plens-Galaska, Martyna, Wesoly, Joanna, Bluyssen, Hans A.R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217051/
https://ncbi.nlm.nih.gov/pubmed/27166190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9195
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