STAT2/IRF9 directs a prolonged ISGF3-like transcriptional response and antiviral activity in the absence of STAT1

Evidence is accumulating for the existence of a signal transducer and activator of transcription 2 (STAT2)/interferon regulatory factor 9 (IRF9)-dependent, STAT1-independent interferon alpha (IFNα) signalling pathway. However, no detailed insight exists into the genome-wide transcriptional regulatio...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Blaszczyk, Katarzyna, Olejnik, Adam, Nowicka, Hanna, Ozgyin, Lilla, Chen, Yi-Ling, Chmielewski, Stefan, Kostyrko, Kaja, Wesoly, Joanna, Balint, Balint Laszlo, Lee, Chien-Kuo, Bluyssen, Hans A.R.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403947/
https://ncbi.nlm.nih.gov/pubmed/25564224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20140644
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