Direct Inhibition of IRF-Dependent Transcriptional Regulatory Mechanisms Associated With Disease

Interferon regulatory factors (IRFs) are a family of homologous proteins that regulate the transcription of interferons (IFNs) and IFN-induced gene expression. As such they are important modulating proteins in the Toll-like receptor (TLR) and IFN signaling pathways, which are vital elements of the i...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Antonczyk, Aleksandra, Krist, Bart, Sajek, Malgorzata, Michalska, Agata, Piaszyk-Borychowska, Anna, Plens-Galaska, Martyna, Wesoly, Joanna, Bluyssen, Hans A. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6543449/
https://ncbi.nlm.nih.gov/pubmed/31178872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01176
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