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PD1 blockade enhances cytotoxicity of in vitro expanded natural killer cells towards myeloma cells
Aiming for an adoptive natural killer (NK) cell therapy, we have developed a novel protocol to expand NK cells from peripheral blood. With this protocol using anti-human CD16 antibody and interleukin (IL)-2, NK (CD3(−)CD56(+)) cells could be expanded about 4000-fold with over 70% purity during a 21-...
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| Опубликовано в: : | Oncotarget |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Impact Journals LLC
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5217023/ https://ncbi.nlm.nih.gov/pubmed/27356741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10235 |
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