Highly activated and expanded natural killer cells for multiple myeloma immunotherapy

BACKGROUND: Patients with gene expression profiling-defined high-risk myeloma in relapse have poor outcomes with current therapies. We tested whether natural killer cells expanded by co-culture with K562 cells transfected with 41BBL and membrane-bound interleukin-15 could kill myeloma cells with a h...

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Main Authors: Garg, Tarun K., Szmania, Susann M., Khan, Junaid A., Hoering, Antje, Malbrough, Paul A., Moreno-Bost, Amberly, Greenway, Amy D., Lingo, Joshuah D., Li, Xin, Yaccoby, Shmuel, Suva, Larry J., Storrie, Brian, Tricot, Guido, Campana, Dario, Shaughnessy, John D., Nair, Bijay P., Bellamy, William T., Epstein, Joshua, Barlogie, Bart, van Rhee, Frits
Formato: Artigo
Idioma:Inglês
Publicado: Ferrata Storti Foundation 2012
Assuntos:
Original Articles and Brief Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436235/
https://ncbi.nlm.nih.gov/pubmed/22419581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.056747
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