Highly activated and expanded natural killer cells for multiple myeloma immunotherapy

BACKGROUND: Patients with gene expression profiling-defined high-risk myeloma in relapse have poor outcomes with current therapies. We tested whether natural killer cells expanded by co-culture with K562 cells transfected with 41BBL and membrane-bound interleukin-15 could kill myeloma cells with a h...

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Autors principals: Garg, Tarun K., Szmania, Susann M., Khan, Junaid A., Hoering, Antje, Malbrough, Paul A., Moreno-Bost, Amberly, Greenway, Amy D., Lingo, Joshuah D., Li, Xin, Yaccoby, Shmuel, Suva, Larry J., Storrie, Brian, Tricot, Guido, Campana, Dario, Shaughnessy, John D., Nair, Bijay P., Bellamy, William T., Epstein, Joshua, Barlogie, Bart, van Rhee, Frits
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2012
Matèries:
Original Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436235/
https://ncbi.nlm.nih.gov/pubmed/22419581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.056747
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