Ex Vivo Expanded Natural Killer Cells Demonstrate Robust Proliferation In Vivo In High-Risk Relapsed Multiple Myeloma Patients

Highly activated/expanded natural killer (NK) cells can be generated via stimulation with the HLA-deficient cell line K562 genetically modified to express 41BB-ligand and membrane-bound interleukin (IL)15. We tested the safety, persistence and activity of expanded NK cells generated from myeloma pat...

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Pubblicato in:J Immunother
Autori principali: Szmania, Susann, Lapteva, Natalia, Garg, Tarun, Greenway, Amy, Lingo, Joshuah, Nair, Bijay, Stone, Katie, Woods, Emily, Khan, Junaid, Stivers, Justin, Panozzo, Susan, Campana, Dario, Bellamy, William T., Robbins, Molly, Epstein, Joshua, Yaccoby, Shmuel, Waheed, Sarah, Gee, Adrian, Cottler-Fox, Michele, Rooney, Cliona, Barlogie, Bart, van Rhee, Frits
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352951/
https://ncbi.nlm.nih.gov/pubmed/25415285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000059
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