The pancreatic niche inhibits the effectiveness of sunitinib treatment of pancreatic cancer

Current treatments for pancreatic ductal adenocarcinoma (PDA) are ineffective, making this the 4(th) leading cause of cancer deaths. Sunitinib is a broad-spectrum inhibitor of tyrosine kinase receptors mostly known for its anti-angiogenic effects. We tested the therapeutic effects of sunitinib in pa...

Full description

Saved in:
Bibliographic Details
Published in:Oncotarget
Main Authors: Martínez-Bosch, Neus, Guerrero, Pedro Enrique, Moreno, Mireia, José, Anabel, Iglesias, Mar, Munné-Collado, Jessica, Anta, Héctor, Gibert, Joan, Orozco, Carlos Alberto, Vinaixa, Judith, Fillat, Cristina, Viñals, Francesc, Navarro, Pilar
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217016/
https://ncbi.nlm.nih.gov/pubmed/27374084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10199
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items