The pancreatic niche inhibits the effectiveness of sunitinib treatment of pancreatic cancer

Current treatments for pancreatic ductal adenocarcinoma (PDA) are ineffective, making this the 4(th) leading cause of cancer deaths. Sunitinib is a broad-spectrum inhibitor of tyrosine kinase receptors mostly known for its anti-angiogenic effects. We tested the therapeutic effects of sunitinib in pa...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Martínez-Bosch, Neus, Guerrero, Pedro Enrique, Moreno, Mireia, José, Anabel, Iglesias, Mar, Munné-Collado, Jessica, Anta, Héctor, Gibert, Joan, Orozco, Carlos Alberto, Vinaixa, Judith, Fillat, Cristina, Viñals, Francesc, Navarro, Pilar
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217016/
https://ncbi.nlm.nih.gov/pubmed/27374084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10199
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