Polo-like kinase 1 inhibition diminishes acquired resistance to epidermal growth factor receptor inhibition in non-small cell lung cancer with T790M mutations

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are effective against non-small cell lung cancer (NSCLC) with activating EGFR mutations, but resistance is inevitable. Mechanisms of acquired resistance include T790M mutations and epithelial–mesenchymal transition (EMT). One...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Wang, Yuehong, Singh, Ratnakar, Wang, Liguang, Nilsson, Monique, Goonatilake, Ruchitha, Tong, Pan, Li, Lerong, Giri, Uma, Villalobos, Pamela, Mino, Barbara, Rodriguez-Canales, Jaime, Wistuba, Ignacio, Wang, Jing, Heymach, John V., Johnson, Faye M.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216995/
https://ncbi.nlm.nih.gov/pubmed/27384992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10332
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars