Epithelial-Mesenchymal Transition Predicts Polo-Like Kinase 1 Inhibitor-Mediated Apoptosis in Non-Small Cell Lung Cancer

PURPOSE: To identify new therapeutic targets for non-small cell lung cancer (NSCLC), we systematically searched 2 cancer cell line databases for sensitivity data on a broad range of drugs. We identified polo-like kinase 1 (PLK1) as the most promising target for further investigation based on a subse...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Clin Cancer Res
Päätekijät: Ferrarotto, Renata, Goonatilake, Ruchitha, Yoo, Suk Young, Tong, Pan, Giri, Uma, Peng, Shaohua, Minna, John, Girard, Luc, Wang, Yuehong, Wang, Liguang, Li, Lerong, Diao, Lixia, Peng, David H., Gibbons, Don L., Glisson, Bonnie S., Heymach, John V., Wang, Jing, Byers, Lauren A., Johnson, Faye M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818738/
https://ncbi.nlm.nih.gov/pubmed/26597303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2890
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