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Epithelial-Mesenchymal Transition Predicts Polo-Like Kinase 1 Inhibitor-Mediated Apoptosis in Non-Small Cell Lung Cancer

PURPOSE: To identify new therapeutic targets for non-small cell lung cancer (NSCLC), we systematically searched 2 cancer cell line databases for sensitivity data on a broad range of drugs. We identified polo-like kinase 1 (PLK1) as the most promising target for further investigation based on a subse...

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Detaylı Bibliyografya
Yayımlandı:Clin Cancer Res
Asıl Yazarlar: Ferrarotto, Renata, Goonatilake, Ruchitha, Yoo, Suk Young, Tong, Pan, Giri, Uma, Peng, Shaohua, Minna, John, Girard, Luc, Wang, Yuehong, Wang, Liguang, Li, Lerong, Diao, Lixia, Peng, David H., Gibbons, Don L., Glisson, Bonnie S., Heymach, John V., Wang, Jing, Byers, Lauren A., Johnson, Faye M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818738/
https://ncbi.nlm.nih.gov/pubmed/26597303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2890
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