RPL27A is a target of miR-595 and may contribute to the myelodysplastic phenotype through ribosomal dysgenesis

We investigated the functional consequences following deletion of a microRNA (miR) termed miR-595 which resides on chromosome 7q and is localised within one of the commonly deleted regions identified for Myelodysplasia (MDS) with monosomy 7 (−7)/isolated loss of 7q (7q-). We identified several targe...

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Vydáno v:Oncotarget
Hlavní autoři: Alkhatabi, Heba A., McLornan, Donal P., Kulasekararaj, Austin G., Malik, Farooq, Seidl, Thomas, Darling, David, Gaken, Joop, Mufti, Ghulam J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216985/
https://ncbi.nlm.nih.gov/pubmed/27374104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10293
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