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Loss of T-cell quiescence by targeting Slfn2 prevents the development and progression of T-ALL
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy of thymocytes. Despite significant improvement in the treatment of T-ALL, approximately 20% of children and most adults undergo relapse. Previous findings demonstrated that loss of T-cell quiescence due to a mutation in the Slfn...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5216906/ https://ncbi.nlm.nih.gov/pubmed/27206675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9390 |
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