Loss of T-cell quiescence by targeting Slfn2 prevents the development and progression of T-ALL

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy of thymocytes. Despite significant improvement in the treatment of T-ALL, approximately 20% of children and most adults undergo relapse. Previous findings demonstrated that loss of T-cell quiescence due to a mutation in the Slfn...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Goldshtein, Aviya, Zerbib, Shani Mistriel, Omar, Ibrahim, Cohen-Daniel, Leonor, Popkin, Daniel, Berger, Michael
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Priority Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216906/
https://ncbi.nlm.nih.gov/pubmed/27206675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9390
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