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Schlafen2 mutation unravels a role for chronic ER stress in the loss of T cell quiescence

Immunologically naïve lymphocytes are kept in a quiescent state until antigen engagement. These quiescent immune cells are characterized by small cell size, lack of spontaneous proliferation and low metabolic rate. Lymphocyte quiescence is actively enforced condition which ensures the preservation o...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Omar, Ibrahim, Lapenna, Antonio, Cohen-Daniel, Leonor, Tirosh, Boaz, Berger, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129940/
https://ncbi.nlm.nih.gov/pubmed/27276683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9818
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