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Targeting cancer stem cells with p53 modulators
Cancer stem cells (CSC) typically over-express aldehyde dehydrogenase (ALDH). Thus, ALDH(bright) tumor cells represent targets for developing novel cancer prevention/treatment interventions. Loss of p53 function is a common genetic event during cancer development wherein small molecular weight compo...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5216707/ https://ncbi.nlm.nih.gov/pubmed/27074569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8650 |
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