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Toward the development of multi-epitope p53 cancer vaccines: an in vitro assessment of CD8(+) T-cell responses to HLA class I-restricted wild-type sequence p53 peptides
Wild-type sequence (wt) p53 peptides are attractive candidates for broadly applicable cancer vaccines. Six HLA-A2 or HLA-A24-restricted wt p53 peptides were evaluated for their ex vivo immunogenicity and their potential for use in cancer vaccines. Peripheral blood mononuclear cells (PBMC) obtained f...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2583371/ https://ncbi.nlm.nih.gov/pubmed/17631051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2007.05.015 |
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