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Discoidin domain receptor 1 promotes Th17 cell migration by activating the RhoA/ROCK/MAPK/ERK signaling pathway

Effector T cell migration through the tissue extracellular matrix (ECM) is an important step of the adaptive immune response and in the development of inflammatory diseases. However, the mechanisms involved in this process are still poorly understood. In this study, we addressed the role of a collag...

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Опубликовано в: :Oncotarget
Главные авторы: Azreq, Mohammed-Amine El, Kadiri, Maleck, Boisvert, Marc, Pagé, Nathalie, Tessier, Philippe A., Aoudjit, Fawzi
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216699/
https://ncbi.nlm.nih.gov/pubmed/27391444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10455
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