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Discoidin domain receptor 1 promotes Th17 cell migration by activating the RhoA/ROCK/MAPK/ERK signaling pathway

Effector T cell migration through the tissue extracellular matrix (ECM) is an important step of the adaptive immune response and in the development of inflammatory diseases. However, the mechanisms involved in this process are still poorly understood. In this study, we addressed the role of a collag...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Azreq, Mohammed-Amine El, Kadiri, Maleck, Boisvert, Marc, Pagé, Nathalie, Tessier, Philippe A., Aoudjit, Fawzi
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216699/
https://ncbi.nlm.nih.gov/pubmed/27391444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10455
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