Identification of genetic modifiers of age-at-onset for familial Parkinson’s disease

Parkinson’s disease (PD) is the most common cause of neurodegenerative movement disorder and the second most common cause of dementia. Genes are thought to have a stronger effect on age-at-onset of PD than on risk, yet there has been a phenomenal success in identifying risk loci but not age-at-onset...

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Bibliografske podrobnosti
izdano v:Hum Mol Genet
Main Authors: Hill-Burns, Erin M., Ross, Owen A., Wissemann, William T., Soto-Ortolaza, Alexandra I., Zareparsi, Sepideh, Siuda, Joanna, Lynch, Timothy, Wszolek, Zbigniew K., Silburn, Peter A., Mellick, George D., Ritz, Beate, Scherzer, Clemens R., Zabetian, Cyrus P., Factor, Stewart A., Breheny, Patrick J., Payami, Haydeh
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Association Studies Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216611/
https://ncbi.nlm.nih.gov/pubmed/27402877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw206
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