Association of Parkinson Disease with Structural and Regulatory Variants in the HLA Region

Historically, association of disease with the major histocompatibility complex (HLA) genes has been tested with HLA alleles that encode antigen-binding affinity. The association with Parkinson disease (PD), however, was discovered with noncoding SNPs in a genome-wide association study (GWAS). We sho...

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Detalhes bibliográficos
Main Authors: Wissemann, William T., Hill-Burns, Erin M., Zabetian, Cyrus P., Factor, Stewart A., Patsopoulos, Nikolaos, Hoglund, Bryan, Holcomb, Cherie, Donahue, Ryan J., Thomson, Glenys, Erlich, Henry, Payami, Haydeh
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824116/
https://ncbi.nlm.nih.gov/pubmed/24183452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.10.009
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