Identification of genetic modifiers of age-at-onset for familial Parkinson’s disease

Parkinson’s disease (PD) is the most common cause of neurodegenerative movement disorder and the second most common cause of dementia. Genes are thought to have a stronger effect on age-at-onset of PD than on risk, yet there has been a phenomenal success in identifying risk loci but not age-at-onset...

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Bibliografiske detaljer
Udgivet i:Hum Mol Genet
Main Authors: Hill-Burns, Erin M., Ross, Owen A., Wissemann, William T., Soto-Ortolaza, Alexandra I., Zareparsi, Sepideh, Siuda, Joanna, Lynch, Timothy, Wszolek, Zbigniew K., Silburn, Peter A., Mellick, George D., Ritz, Beate, Scherzer, Clemens R., Zabetian, Cyrus P., Factor, Stewart A., Breheny, Patrick J., Payami, Haydeh
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Association Studies Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216611/
https://ncbi.nlm.nih.gov/pubmed/27402877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw206
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