Membrane translocation of t-SNARE protein syntaxin-4 abrogates ground-state pluripotency in mouse embryonic stem cells

Embryonic stem (ES) and induced pluripotent stem (iPS) cells are attractive tools for regenerative medicine therapies. However, aberrant cell populations that display flattened morphology and lose ground-state pluripotency often appear spontaneously, unless glycogen synthase kinase 3β (GSK3β) and mi...

Full description

Saved in:
Bibliographic Details
Published in:Sci Rep
Main Authors: Hagiwara-Chatani, Natsumi, Shirai, Kota, Kido, Takumi, Horigome, Tomoatsu, Yasue, Akihiro, Adachi, Naoki, Hirai, Yohei
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216394/
https://ncbi.nlm.nih.gov/pubmed/28057922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39868
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items