Membrane translocation of t-SNARE protein syntaxin-4 abrogates ground-state pluripotency in mouse embryonic stem cells

Embryonic stem (ES) and induced pluripotent stem (iPS) cells are attractive tools for regenerative medicine therapies. However, aberrant cell populations that display flattened morphology and lose ground-state pluripotency often appear spontaneously, unless glycogen synthase kinase 3β (GSK3β) and mi...

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Vydáno v:Sci Rep
Hlavní autoři: Hagiwara-Chatani, Natsumi, Shirai, Kota, Kido, Takumi, Horigome, Tomoatsu, Yasue, Akihiro, Adachi, Naoki, Hirai, Yohei
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216394/
https://ncbi.nlm.nih.gov/pubmed/28057922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39868
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