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Membrane translocation of t-SNARE protein syntaxin-4 abrogates ground-state pluripotency in mouse embryonic stem cells

Embryonic stem (ES) and induced pluripotent stem (iPS) cells are attractive tools for regenerative medicine therapies. However, aberrant cell populations that display flattened morphology and lose ground-state pluripotency often appear spontaneously, unless glycogen synthase kinase 3β (GSK3β) and mi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hagiwara-Chatani, Natsumi, Shirai, Kota, Kido, Takumi, Horigome, Tomoatsu, Yasue, Akihiro, Adachi, Naoki, Hirai, Yohei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216394/
https://ncbi.nlm.nih.gov/pubmed/28057922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39868
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