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The SNARE Motif Is Essential for the Formation of Syntaxin Clusters in the Plasma Membrane

In the plasma membrane, syntaxin 1 and syntaxin 4 clusters define sites at which secretory granules and caveolae fuse, respectively. It is widely believed that lipid phases are mandatory for cluster formation, as cluster integrity depends on cholesterol. Here we report that the native lipid environm...

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Detalhes bibliográficos
Main Authors: Sieber, Jochen J., Willig, Katrin I., Heintzmann, Rainer, Hell, Stefan W., Lang, Thorsten
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1414554/
https://ncbi.nlm.nih.gov/pubmed/16443657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.079574
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